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Boosting Dairy Cattle Fertility: The Future of Genetic Selection for Modern Farmers

Boost your dairy herd’s fertility with cutting-edge genetic selection. Discover how modern techniques can enhance pregnancy rates and streamline your farm’s operations.

Consider a dairy farm where cows get pregnant shortly after calving with minimum manipulations. This is not a pipe dream; deliberate fertility selection may make it a reality. High fertility in dairy farming leads to shorter calving intervals, improved milk production cycles, and increased profitability.

Rapid pregnancy following calving is critical for a robust herd and sustainable operations. Pregnancy consists of various stages: the uterus returns to normal after birth, estrous cycles resume, and estrus is recognized. Sperm is subsequently placed and capacitated, ovulation and fertilization occur, and the corpus luteum generates progesterone to keep the pregnancy going. Each phase is heritable and necessary for a successful pregnancy after insemination.

Prioritizing fertility benefits dairy producers by reducing inseminations, lowering veterinary expenses, and increasing herd output. The potential for profitability via genetic selection for features that ensure fast pregnancy after insemination has the potential to change dairy production. This realistic method may improve dairy operations, offering farmers hope and motivation.

Overcoming Fertility Challenges in Modern Dairy Farming: A Path to Sustainability and Profitability 

Modern dairy producers have substantial reproductive issues critical for profitability and sustainability. Reducing the number of inseminations required for pregnancy is vital since each additional effort increases expenses and extends the calving interval, affecting milk output and herd efficiency. ‘Days open,’ or the time from calving to successful insemination is essential in fertility control. Quick pregnancy establishment after calving is critical; delays in uterine involution and estrous cycle re-establishment might impair fertility.

Accurate estrus identification is crucial for maximizing breeding chances and reducing days open. Reproductive management approaches vary in efficacy and depend on cow circumstances and farm management practices. Some systems utilize natural estrus detection, while others use hormonal therapies such as PGF2α and GnRH with timed AI.

Genetics has a significant impact on fertility. While selection tries to minimize the number of days open, the diversity of dairy systems implies that favorable features in one system may not transfer well into another. Understanding reproductive genetics and their interaction with various management approaches is essential for making educated breeding choices. This information gives dairy producers greater confidence and control over their operations.

Achieving high fertility in dairy cows requires careful reproductive management, precise estrus detection, and a thorough grasp of genetics. This knowledge includes identifying heritable features and considering their interactions and possible trade-offs when making breeding choices. Addressing these factors may improve herd reproductive performance, resulting in more sustainable and profitable farming.

The Journey from Uterine Involution to Progesterone Production: A Symphony of Reproductive Success 

The first phase following calving is uterine involution, which restores the uterus to its pre-pregnancy condition and lays the groundwork for future reproductive cycles. After involution, the cow’s reproductive system returns to regular menstrual cycles, preparing for future pregnancies.

The next step involves detecting and expressing estrus. Estrus, sometimes known as ‘heat,’ occurs when a cow is sexually receptive and pregnant. Properly detecting this phase is critical for effective insemination. During estrus, sperm enter the cow’s reproductive canal and undergo capacitation. This process allows the sperm to penetrate and fertilize the egg.

Following capacitation, ovulation occurs when an egg from the ovary enters the oviduct and meets the capacitated sperm. Fertilization is the process of combining sperm and egg to form an embryo. After fertilization, the corpus luteum develops on the ovary and produces progesterone, essential for pregnancy and embryonic development.

Each process, from uterine involution to progesterone production, is critical for obtaining and maintaining pregnancy in dairy cows. Understanding and improving biological processes may boost fertility rates, increasing production and profitability in dairy farming.

Delving into the Heritability of Fertility Traits: From Uterine Involution to Embryo Development 

Exploring the heritability of fertility characteristics requires understanding how each event in the reproductive sequence contributes to the overall fertility phenotype in dairy cows. This process, which begins with uterine involution, characterizes the early postpartum period and is crucial for restoring normal reproductive function. Genetic variables impacting the rate and effectiveness of uterine involution may be heritable, possibly decreasing the time between calving and the following successful pregnancy.

Another critical event is the restoration of estrous cycles. The capacity to resume regular estrous cycles promptly significantly impacts conception rates. Genetic variation affecting the timing and regularity of these cycles is most certainly heritable, influencing how easily and quickly cows may be inseminated again.

The next step is estrus expression and detection. Cows with apparent indications of estrus are more likely to be effectively inseminated. Traits related to estrus expression, such as the strength and length of behavioral indicators, may be handed down across generations, influencing fertility.

Sperm deposition and capacitation in the reproductive tract are equally important. Efficient sperm capacitation for conception requires both male and female genetic contributions. Genes that affect the uterine environment and sperm cell function may increase the chances of successful sperm capacitation and subsequent conception.

Ovulation, an important occurrence, is governed by hormone cycles and is genetically controlled. The time and predictability of ovulation may be chosen, resulting in more effective inseminations. Following ovulation, the creation and function of the corpus luteum (CL), which generates progesterone, is crucial for pregnancy maintenance. Heritable features that promote robust CL development and sufficient progesterone production are critical for establishing and maintaining pregnancy.

Beyond these phases, the oviduct’s involvement in promoting embryonic cleavage and the uterus’ formation of a receptive environment is potentially heritable. Genetic predispositions that favor specific settings may increase embryo survival and development, eventually enhancing fertility rates.

The phenotypic manifestation of fertility in dairy cows comprises many heritable variables, each influencing a particular event in the reproductive process. Selection for these qualities may increase total fertility, making genetic knowledge and selection an essential component of sustainable and lucrative dairy production.

Optimizing “Days Open”: The Pinnacle of Genetic Selection for Enhanced Dairy Cow Fertility

Genetic selection for fertility in dairy cows primarily focuses on minimizing the number of days between calving and pregnancy, sometimes known as “days open.” This statistic is important because it captures the overall influence of several specific fertility components. Each stage of the reproductive process—from uterine involution, re-establishment of estrous cycles, and successful ovulation to efficient sperm capacitation, fertilization, and the creation of a functioning corpus luteum—is critical in determining whether a cow gets pregnant following insemination. By concentrating on lowering the number of days open, dairy producers and geneticists select cows more efficiently, restarting reproductive cycles and effectively conceiving after calving. This complete method guarantees that selection pressures are equally dispersed, resulting in improved reproductive features for sustainable and prosperous dairy production.

Customizing Reproductive Strategies: Navigating Between Minimal Intervention and Intensive Management Systems 

In dairy farming, reproductive management is vital in determining fertility and total herd output. Different approaches improve breeding efficiency, each with unique benefits and uses. Minimal intervention approaches, for example, depend heavily on recognizing natural estrus. Cows in such systems are watched for indicators of estrus, such as mounting behavior or increased activity, and insemination occurs once estrus is recognized. This strategy may improve breeding accuracy by inseminating cows when they are most fertile, perhaps lowering the number of inseminations necessary for pregnancy. However, detecting modest estrus symptoms requires tremendous effort and experience.

On the other side, more extensive reproductive management approaches include hormone therapies and scheduled artificial insemination (AI). To synchronize a group of cows’ reproductive cycles, procedures may consist of giving PGF2α to induce luteolysis and GnRH to trigger ovulation. This synchronization enables timed AI, where insemination happens at a particular time regardless of obvious estrus signals. This strategy has the benefit of being consistent and predictable, which might lead to increased conception rates and more efficient herd management. Nonetheless, this strategy requires exact timing, extra hormone expenses, and strict protocol adherence.

The dairy operation’s unique demands and capacity determine the decision between minimum intervention and extensive reproductive management methods. Minimal intervention techniques may be more practical for smaller herds with enough manpower. At the same time, larger operations may benefit from the efficiency and consistency of timed AI protocols. Understanding each system’s strengths and limitations is critical for improving reproductive results and unlocking the genetic potential of contemporary dairy cows.

Different Management Systems, Different Genetic Pressures: Strategizing ‘Days Open’ for Optimal Fertility 

Different reproductive management systems provide different stresses to the specific fertility components, impacting the selection process for days. Cows are inseminated mainly after estrus is identified in minimum intervention systems, stressing the cow’s inherent ability to have regular cycles and evident symptoms of estrus. Days open to become a composite metric representing several distinct fertility qualities, including estrus detection, sperm capacitation, and ovulation time. Genetic selection in these systems promotes features associated with high natural reproductive success and low human intervention.

In contrast, rigorous management methods that include hormonal therapies like PGF2α and GnRH, followed by scheduled artificial insemination (AI), shift the relevance of reproductive features. In this context, characteristics such as responsiveness to hormone therapies and scheduled AI cycle success rates are relevant. Days open remain crucial, but the various fertility components contributing to it may be weighted differently. For example, the precision and timing of ovulation caused by hormonal treatments may become more important than natural estrus-detecting skills.

Such variances demand a detailed knowledge of fertility genetics to choose cows that perform consistently well across various reproductive management measures. Adaptive genetic selection may retain fertility features across farm operations, leading to better reproductive success and profitability for dairy herds.

Genetic Insights: Paving the Way for Uniform Fertility Performance in Diverse Dairy Management 

Obtaining consistent fertility performance across diverse reproductive management systems will demand a more in-depth knowledge of the genetics of each fertility component. This involves more than simply examining surface-level features; it also necessitates looking into the genetic markers and pathways that regulate each stage of the reproduction process. By identifying and comprehending these genetic characteristics, dairy producers may choose cows that perform well under minimum intervention systems while excelling under more extensive, hormone-based management schemes. Such insights might lead to the establishment of customized breeding plans adapted to the individual needs of various dairy farming operations, improving the herd’s sustainability and profitability. Advanced genomic techniques and technology will be critical in this effort, providing unparalleled accuracy in selecting and breeding tactics. This integrated strategy may improve the reproductive efficiency of dairy cows, leading to a more resilient and productive dairy sector.

Key Takeaways:

  • The primary definition of fertility in dairy systems is the establishment of pregnancy post-insemination.
  • Highly fertile cows establish pregnancy sooner after calving, requiring fewer inseminations.
  • Fertility involves several sequential events: uterine involution, re-establishment of estrous cycles, expression and detection of estrus, sperm capacitation, ovulation, fertilization, and corpus luteum progesterone production.
  • Each fertility event is potentially heritable, collectively contributing to the pregnancy phenotype after insemination.
  • Genetic selection for fertility often focuses on reducing the “days open” period.
  • Dairy systems use varied reproductive management strategies, from minimal intervention to intensive hormonal treatments.
  • Selection pressures on fertility components may differ across systems, impacting overall fertility outcomes.
  • Uniform performance of cows in diverse management systems requires a deeper understanding of the genetic underpinnings of fertility traits.

Summary:

High fertility in dairy farming can lead to shorter calving intervals, improved milk production cycles, and increased profitability. Pregnancy involves various stages, including uterine involution, estrous cycle restoration, estrus recognition, sperm placement, ovulation and fertilization, and progesterone production. Prioritizing fertility benefits dairy producers by reducing inseminations, lowering veterinary expenses, and increasing herd output. Genetic selection for fast pregnancy after insemination can change dairy production, providing farmers with hope and motivation. Reproductive issues are critical for profitability and sustainability, with reducing inseminations increasing costs and affecting milk output and herd efficiency. Understanding reproductive genetics and their interaction with management approaches is essential for making educated breeding choices and improving herd reproductive performance, resulting in more sustainable and profitable farming.

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U.S. Dairy Farm Profits Surge to 18-Month High Amid Challenges

U.S. dairy farm profits have soared to their highest in 18 months, but there are still challenges. What is driving this growth and what obstacles do producers face?

The U.S. dairy sector is poised for expansion, with producer margins at their most significant level in eighteen months. The Dairy Margin Coverage (DMC) program, which measures the ‘Milk Margin Above Feed Costs,’ shows a favorable trend. The most significant margin since November 2022, the Milk Margin Above Feed Costs, shot to $10.52 per hundredweight (cwt), a 92-cent rise from April. This influences dairy producers’ production choices and indicates improved circumstances, paving the way for potential expansion.

While growing margins are welcome news for dairy farmers, it’s crucial to recognize the significant obstacles. These include persistent animal health problems, high funding expenses, and the absence of replacement animals. However, it’s important to note that the more long-standing margins remain at current levels, the more likely resourceful producers will be able to overcome these obstacles and boost output. This presents both possibilities and challenges for the dairy sector, underscoring the crucial role of innovation in overcoming barriers and driving growth.

Despite obstacles like animal health concerns, expensive finance, and the absence of replacement animals, the dairy sector is poised for growth. The consistently high profits imply creative producers might discover ways to increase production. This growth potential should encourage stakeholders and inspire them to explore new opportunities in the dairy industry.

May’s Leap in Milk Margins Signals Robust Fortunes for Dairy Producers

Rising to $10.52/cwt, May’s Milk Margin Above Feed Costs jumped 92 cents from April and had the most significant margin since November 2022. This increase points to a favorable trend for dairy farmers, providing a counter against market instability. The Dairy Margin Coverage (DMC) scheme pays farmers when margins fall short of $9.50/cwt. May was notably the third month without prompted payments, demonstrating the industry’s improved profitability.

A Closer Look at May’s Favorable Milk Pricing and Moderating Feed Costs 

Lower feed costs and better milk prices are mainly responsible for rising dairy producer margins. Rising $1.50 from April, the highest since January 2023, the All-Milk price in May hit $22/cWT. The Class III price was significant, which rose by more than $3/cwt. Together with increases in the Class IV price, this rise in Class III pricing significantly raised general milk costs.

From April to $11.48/cwt in May, feed expenses rose marginally, climbing 58 cents. Still, they come out at almost $3/cwt, less than the previous year. These savings are remarkable due to growing maize, soybean meal, and premium alfalfa costs. Notwithstanding these increases, the general trend indicates a notable drop in feed prices from past years, relieving dairy farmers of financial burden.

Challenges Clouding Dairy Expansion Despite Higher Margins 

Although growing dairy margins provide hope, significant challenges limit growth. Still a major problem, animal health affects milk output and results in substantial veterinary expenses.

High interest rates—often around five percent—make borrowing costly, hampering development strategies. Declining basic salaries and the expense of following strict water and environmental rules aggravate financial hardship.

The lack of quality replacement animals further hinders growth initiatives. Restricted availability increases acquisition expenses, making it challenging even with larger margins. Navigating these challenges calls for creative and strategic solutions for American dairy companies to profit appropriately from present economic times.

Projecting the Future: Market Dynamics and Anticipated Shifts in Class III Milk Prices

Future markets provide a critical window into the anticipated pricing course for Class III milk specifically. Future contract data point to likely declining prices. Although dairy product spot prices are still high, futures markets project reduced values. This is especially pertinent for Class III pricing as, after recent increases, it might soon be under downward pressure.

Factors like rising supply, changing world demand, and economic variables, including feed costs and export tendencies, might cause the anticipated decline in Class III pricing. Although manufacturers have benefited from more margins lately, should these predictions come true, they might have to be ready for less earnings. But how much the effect of reduced pricing is felt will depend on your capacity to adjust with sensible cost control and planned market activities.

Contrasting Fortunes: Robust Domestic Margins Meet Declining Dairy Exports 

USDA’s Foreign Agricultural Service reported that U.S. dairy exports showed a different picture in May, falling 1.7% below previous-year levels within domestic solid margins. Reflecting slow worldwide demand, total exports came to 504.8 million pounds.

With nearly 40 million pounds sent to Mexico, cheese exports rose by 46.6% despite this drop, reaching a new high for May at 504.8 million pounds. Whey exports also rose by 15.2% in response to growing demand from China.

On the negative side, butter exports dropped 19.4% under high prices, and nonfat dry milk exports fell 24.2%. These conflicting findings highlight the brutal global scene U.S. dairy farmers have to negotiate.

The Bottom Line

The U.S. dairy sector is experiencing a significant upturn, with the highest margins in 18 months and controlled feed prices. These recent margin improvements provide financial respite and instill a sense of optimism. However, it’s essential to acknowledge the ongoing obstacles—such as animal health issues, expensive finance, and a shortage of replacement animals—limiting farmers’ potential gains. This mixed view, with local solid success but diminishing foreign exports, underscores the industry’s complex future. Creative and resourceful producers are best positioned to leverage these profitable margins for expansion. The ability to address these issues and explore new approaches for growth and resilience will ultimately determine the fate of U.S. dairy operations. Now is the time for producers to be innovative and ensure their businesses remain profitable and future-ready.

Key Takeaways:

  • Dairy producer margins have climbed to their highest level in a year and a half, with May’s Milk Margin Above Feed Costs reaching $10.52/cwt.
  • Stronger milk prices, particularly increases in Class IV and Class III prices, played a significant role in enhancing producer margins.
  • Feed costs, although rising slightly in May, remain considerably lower than the elevated levels seen in previous years.
  • Barriers such as animal health issues, expensive financing, and a lack of replacement animals hinder dairy producers’ ability to scale up production despite higher margins.
  • U.S. dairy exports saw a decline in May, primarily due to weak demand from Asia, even as exports to Mexico surged.
  • Cheese exports reached a record high for May, while other dairy categories like nonfat dry milk and butter experienced declines.

Summary:

The U.S. dairy sector is experiencing significant growth, with producer margins at their highest level in 18 months. The Milk Margin Above Feed Costs program shows a favorable trend, with the Milk Margin Above Feed Costs rising to $10.52 per hundredweight (cwt), a 92-cent rise from April. This indicates improved circumstances and potential expansion for dairy producers. However, significant obstacles such as persistent animal health problems, high funding expenses, and the absence of replacement animals remain. Despite these challenges, the dairy sector is poised for growth, with consistently high profits suggesting creative producers might discover ways to increase production. Lower feed costs and better milk prices are mainly responsible for rising dairy producer margins. However, significant challenges cloud dairy expansion, including animal health, high interest rates, declining basic salaries, and the lack of quality replacement animals.

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Global Dairy Cattle Diseases Cost $65 Billion Annually: India, US, and China Hit Hardest

Learn how dairy cattle diseases cost the world $65 billion every year. Which countries suffer the most and why? Uncover the detailed findings now.

The 340 cows at Philipsen Farms dairy near Lacombe, Alta., are milked three times a day. All are registered Holsteins.

With yearly losses at a staggering $65 billion, dairy cow illnesses are not just a local concern but a global economic crisis. The impact is felt in every corner of the world, from India to the United States to China and beyond. These losses disrupt milk production, lower fertility, and directly affect the livelihoods of countless farmers. This is not just a statistic but a pressing issue that demands immediate attention.

Though these costs vary greatly worldwide, “the total annual global losses due to dairy cattle diseases are greatest in India, the US, and China.”

Investigate the financial ruin dairy cow illnesses like mastitis, ketosis, and lameness cause. This study provides a thorough worldwide view and uncovers why specific ailments are more expensive than others.

The Hidden Costs of Dairy Cattle Diseases: An In-Depth Global Economic Analysis

Under the direction of Philip Rasmussen of the University of Copenhagen, a team of researchers has conducted a thorough and innovative study reported in the Journal of Dairy Science that offers a comprehensive worldwide economic evaluation of dairy cow illnesses. Examining statistics from more than 180 milk-producing nations, the research painstakingly examines the financial impact of 12 major dairy cow illnesses and health issues. The researchers not only precisely calculated the worldwide losses using a comorbidity-adjusted technique but also guaranteed that any overlaps in illness effects were considered, hence providing a more accurate estimate. This thorough investigation emphasizes the global broad and different economic load dairy cow illnesses cause.

Twelve major dairy cow diseases, including mastitis (subclinical and clinical), lameness, paratuberculosis, displaced abomasum, dystocia, metritis, milk fever, ovarian cysts, retained placenta, and ketosis (clinical and subclinical), were investigated economically. These illnesses raise culling rates, affect milk output, and change reproductive rates. Precise approximations of their effects enable improved control and lower financial losses.

With a comorbidity-adjusted economic analysis, the researchers painstakingly calculated the cost of dairy cow illnesses. They considered characteristics like milk output, fertility, and culling rates, and compiled data on twelve illnesses from literature covering over 180 milk-producing countries. They standardized these measures for consistent comparability across research to guarantee dependability. This rigorous methodology ensures the accuracy and reliability of our findings.

They then combined these datasets into thorough estimations using sophisticated meta-analysis methods ranging from basic averaging to complicated random-effects models. Correcting for comorbidities was essential to avoid overestimation and to recognize the concurrent incidence of many illnesses with their combined financial consequences.

Equipped with these consistent projections, the group modeled the financial influence using Monte Carlo simulations. They precisely estimated the economic losses by including country-specific data on illness incidence, lactational prevalence, herd features, and economic criteria.

This study depends on adjusting for comorbidities to guarantee that overlapping health problems do not distort the economic effects of different illnesses. Dairy cow infections often coexist and cause combined health problems that distort statistics. Considering these comorbidities helped researchers to estimate the cost more precisely. Without this change, 45% of the worldwide losses would have been exaggerated, distorting the actual economic weight of the dairy sector. This change offers a more accurate knowledge of the financial effects related to illnesses of dairy cattle.

Dairy Cattle Diseases: A $65 Billion Annual Burden with Subclinical Ketosis and Mastitis Leading the Costs

According to an extensive analysis of dairy cow illnesses, yearly worldwide losses amount to US$65 billion. Most importantly, subclinical ketosis, clinical mastitis, and subclinical mastitis surfaced as the most expensive causes of mean annual worldwide losses, ranging from US$18 billion to US$13 billion and US$9 billion, respectively.

DiseaseGlobal Losses (US$ Billion)India (US$ Billion)US (US$ Billion)China (US$ Billion)
Subclinical Ketosis183.62.41.5
Clinical Mastitis132.61.81.1
Subclinical Mastitis91.81.20.75
Clinical Ketosis0.20.040.030.02
Displaced Abomasum0.60.120.080.05
Dystocia0.60.120.080.05
Lameness61.20.80.5
Metritis510.670.42
Milk Fever0.60.120.080.05
Ovarian Cysts40.80.530.32
Paratuberculosis40.80.530.32
Retained Placenta30.60.40.25

In China, the United States, and India, dairy cow illnesses have a negative economic influence. With $12 billion yearly losses, India’s dairy industry’s great size emphasizes the necessity of improved disease control, and the country suffers the most. Veterinary expenses, decreased milk output, and early culling cause the United States to lose $8 billion annually. With China’s industrial-scale dairy production and rising demand for dairy products, its $5 billion losses reflect its industrial nature.

The financial burden of these losses is defined by various measures. When viewed as a proportion of GDP, India’s agricultural economy bears the brunt, highlighting the need for tailored disease control plans. Analyzing losses per capita or as a proportion of overall milk income offers another perspective. The high dairy output quantities underscore the potential for significant financial losses even with a low frequency of illness. This underscores the necessity of customized disease control plans, designed to fit the unique architecture and economic situation of each nation’s dairy sector.

The Bottom Line

This study emphasizes the important role that legislators, scientists, and dairy industry stakeholders play globally. With nearly half of these costs ascribed to subclinical ketosis, clinical mastitis, and subclinical mastitis, it exposes the shockingly high financial cost of dairy cow diseases—$65 billion yearly. The research shows how urgently policies and focused treatments are needed. Countries with the most losses—China, the US, and India—have to lead in putting sensible disease management strategies into effect. Best agricultural techniques, better veterinary care, and strong monitoring systems may help to greatly reduce these losses. All those involved must recognize and solve these financial challenges, thereby guaranteeing the viability of the worldwide dairy sector.

Key Takeaways:

  • Global dairy cattle diseases lead to annual financial losses of approximately US$65 billion, affecting milk yield, fertility, and culling rates.
  • The most significant losses are observed in India (US$12 billion), the US (US$8 billion), and China (US$5 billion).
  • Subclinical ketosis, clinical mastitis, and subclinical mastitis were identified as the costliest diseases, with annual global losses of US$18 billion, US$13 billion, and US$9 billion, respectively.
  • When adjusting for comorbidities, the overestimation of aggregate global losses is reduced by 45%, highlighting the importance of considering disease interactions.
  • Disease-specific losses include lameness (US$6 billion), metritis (US$5 billion), ovarian cysts (US$4 billion), paratuberculosis (US$4 billion), and retained placenta (US$3 billion).
  • The relative economic burden of dairy cattle diseases varies significantly across countries, dependent on metrics such as GDP, per capita losses, and gross milk revenue.
  • Effective and customized disease control plans are essential to mitigate these substantial economic impacts.

Summary: Dairy cow diseases, causing $65 billion in yearly losses, are a global economic crisis affecting milk production, fertility, and farmers’ livelihoods. The largest losses are in India, the US, and China. A study by Philip Rasmussen of the University of Copenhagen evaluated the financial impact of 12 major dairy cow diseases, including mastitis, lameness, paratuberculosis, displaced abomasum, dystocia, metritis, milk fever, ovarian cysts, retained placenta, and ketosis. These diseases increase culling rates, affect milk output, and change reproductive rates. India’s dairy industry suffers the most, with $12 billion yearly losses. The US loses $8 billion annually due to veterinary expenses, decreased milk output, and early culling. China’s industrial-scale dairy production and rising demand result in $5 billion losses. Customized disease control plans are necessary to address these losses.

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