Archive for Johne’s disease

New Testing Strategies for Dairy Calves Can Reduce Johne’s Disease by 30%

Johne’s disease costs dairy farmers millions annually, but new research shows calves may be key to stopping its spread. Advanced diagnostics and better management practices could cut transmission by 30%, saving herds and profits. Learn how these game-changing strategies can protect your farm!

Summary:

Johne’s disease (JD) remains a costly challenge for dairy farmers, but recent advancements in diagnostics and management strategies offer hope. A new review highlights the importance of including calves and heifers in testing programs, as up to 40% of new infections occur in young stock. Tools like fecal PCR and ELISA enable earlier detection, while improved hygiene practices, such as colostrum management and separating infected animals, can reduce transmission by up to 30%. With JD costing the U.S. dairy industry $200–250 million annually, adopting these strategies could significantly improve herd health and profitability.

Key Takeaways:

  • Inclusion of calves and heifers in Johne’s disease testing can reduce transmission by 30%.
  • Advanced diagnostic tools, such as fecal PCR and phage-based tests, improve early detection accuracy.
  • Better management practices, including improved hygiene and colostrum management, significantly lower infection rates.
  • Early testing and segregation of infected animals can help farmers save up to $500 per cow on culling costs.
  • Economic losses from Johne’s disease can reach $40-$200 per cow annually, affecting overall farm profitability.

A recent review in the Journal of Dairy Science reveals that including calves and heifers in Johne’s disease (JD) testing has been a critical gap in control programs. Including young stock in testing strategies could reduce Johne’s disease (JD) transmission by up to 30%, potentially saving dairy farms thousands of dollars annually in lost productivity and culling costs. 

Young Stock: The Key to Breaking the Cycle 

Johne’s disease, caused by Mycobacterium avium subspecies paratuberculosis (MAP), is a chronic bacterial infection that damages cattle intestines. This leads to reduced milk production, fertility issues, and premature culling. Historically, control programs have focused on adult cattle, but new evidence shows that adult cattle are highly susceptible to Johne’s disease infection. 

Studies indicate that up to 40% of new JD infections occur in calves under six months old, often through contact with contaminated manure, milk, or colostrum from infected cows. Calves can shed MAP bacteria much earlier than previously thought. We’re missing a critical opportunity to stop Johne’s disease from spreading by excluding calves from testing.

Advanced Diagnostics: Detecting JD Earlier 

Diagnostic ToolWhat It DetectsAccuracyAge of UseCost (Approx.)Key Advantage
Fecal PCRMAP DNA in feces~90%4 months and older$32 per sampleHigh accuracy; detects early shedding
Phage-Based TestsLive MAP bacteria~75–85%4 months and olderVariesReduces false negatives by 25%
ELISA Blood TestsMAP-specific antibodies~70–80%8–12 weeks post-infection$6–10 per testCost-effective for large groups
Interferon-Gamma Assay (IGRA)Immune response to MAP~80%Heifers and adultsHigher than ELISADetects early immune responses


New diagnostic tools, such as fecal PCR, phage-based tests, and ELISA blood tests, make it possible to identify MAP infections in calves and heifers much earlier. These include: 

  • Fecal PCR: Detects MAP DNA with up to 90% accuracy and can identify infected calves as young as four months old.
  • Phage-Based Tests: These tests use viruses that target live MAP bacteria, reducing false negatives by 25% compared to traditional methods.
  • ELISA Blood Tests: Identify immune responses to MAP within 8–12 weeks of infection and are cost-effective for screening large groups of animals.

These tools allow us to catch infections early before they cause significant damage. Studies from the Wisconsin Department of Agriculture have shown that early detection of Johne’s disease could reduce culling costs by up to $227 per cow. 

“High sensitivity, rapid turnaround, and reasonable fees make fecal PCR the test of choice for clinical suspects.” (Cornell University Veterinary Diagnostic Center).

Hygiene and Management: Practical Steps for Farmers 

Management PracticeWhat It PreventsKey Benefit
Remove calves from contaminated areas within 1 hour of birthMAP exposure via manureReduces infection risk significantly
Use pasteurized colostrum or test milk from dams for MAPMAP transmission through milk/colostrumEnsures safe feeding practices
Segregate positive animalsDirect contact with infected animalsMinimizes spread within the herd

Testing alone isn’t enough—effective management practices are critical for reducing JD transmission among young stock. The review highlights three key strategies: 

  1. Improve Hygiene: To prevent exposure to MAP bacteria, newborn calves should be removed from contaminated areas within one hour of birth.
  2. Colostrum Management: Use pasteurized colostrum or test milk from dams for MAP before feeding it to calves.
  3. Segregate Positive Animals: Move test-positive heifers into separate groups to minimize contact with healthy animals.

According to case studies cited in the review, farmers who adopt these practices alongside testing have observed infection rates drop by up to 15% annually. 

“Pooling colostrum in infected herds increases the risk of infecting calves, even when cows have tested negative for MAP.” (Welsh Government Guidance on Johne’s Disease).

Economic Impact of JD on Dairy Farms 

Impact AreaEstimated Cost
Loss per Infected Cow (Mild Cases)$33 annually (milk production loss)
Loss per Infected Cow (Clinical Cases)$227 annually (culling/replacement costs)
U.S. Dairy Industry Total Losses$200–250 million annually

Johne’s disease is costly for dairy farms worldwide, with infected herds losing an estimated $33 per cow annually due to reduced milk production and premature culling. Infected herds lose an estimated $33 per cow annually due to reduced milk production and premature culling. For herds with high clinical cull rates, losses can reach $227 per cow annually, including decreased slaughter value and increased replacement costs. 

Johne’s disease costs the U.S. dairy industry between $200 million and $250 million annually, making it one of the most economically significant cattle diseases. 

“In U.S. dairy herds with more than 10% of culls showing clinical signs, annual production losses were $227 per cow, with reduced milk production accounting for most of the loss.” (Province of Manitoba Agriculture).

Challenges and Considerations for Farmers 

While these advancements are promising, implementing them comes with challenges: 

  • The cost of diagnostics, such as fecal PCR tests, which cost around $32 per sample, may be prohibitive for smaller farms without the option to pool samples.
  • Labor Requirements: Regular testing and implementing strict hygiene protocols, which require additional time and resources.
  • False Positives/Negatives: No diagnostic tool is perfect; occasional errors may require follow-up tests or adjustments to herd management plans.

Dairy farms must balance short-term costs and long-term benefits to manage Johne’s disease effectively.

“Not enough herds are participating in serious JD control programs, and almost no herds are using proper biosecurity measures to avoid buying M. paratuberculosis-infected cattle.” (Dr. Mike Collins, University of Wisconsin).

A Path Toward Eradication? 

Researchers believe that including young stock in control programs could significantly reduce the prevalence of JD over time, contributing to the long-term goal of eradicating the disease. They recommend farmers take these steps now: 

  1. Test at least 10% of young stock quarterly using advanced diagnostics like fecal PCR or ELISA blood tests.
  2. Collaborate with veterinarians to develop farm-specific testing schedules and management strategies.
  3. Advocate for more research into JD vaccines for calves and heifers, which could further reduce infection rates.

Johne’s disease is one of the most significant hidden costs in dairy farming.  You can protect future herds by acting early, starting with today’s calves.

“Within a year of participating in the Johne’s Disease Control Demonstration Project, we reduced Johne’s disease prevalence in half. By the end of the study, we had virtually eliminated it from our herd.” (Beth Ingraham, organic dairy farmer).

Why This Matters for Your Farm 

Johne’s disease represents both a financial burden and a management challenge for dairy farmers. By integrating young stock into testing programs and adopting better hygiene practices, farms can reduce infection rates while improving productivity and profitability. 

Call to Action 

Are you ready to take control of Johne’s disease on your farm? Consult your veterinarian about advanced diagnostic tools like fecal PCR or ELISA tests for your young stock program. Visit the Journal of Dairy Science for more details on this groundbreaking research. 

Consider how you will adapt these strategies on your farm and take proactive steps to implement them. 

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Revolutionary Phage Therapy Approach Offers New Hope for Controlling Johne’s Disease

Discover how new phage therapy could change Johne’s disease control in dairy herds. Will this breakthrough help herd health and increase farm profits?

Johne’s disease is a significant problem for dairy farms worldwide. It is caused by a sneaky bacterium called Mycobacterium avium subspecies paratuberculosis (MAP). This disease spreads slowly and quietly, leading to significant money losses and harming animal health. Traditional methods often do not work, so farmers look for better solutions. A new study offers hope with phage therapy, which might help manage Johne’s disease. Researchers at the University of Calgary discovered that using bacteriophages—unique viruses that attack certain bacteria—can protect young calves from MAP infection. 

“Johne’s disease is often hidden in dairy farms. By the time you see signs, the sick animal might have been spreading the disease for years,” says Dr. Jeroen De Buck, the lead researcher.

If phage therapy proves effective on a larger scale, it could significantly enhance herd health by halting the spread of Johne’s disease. This could increase dairy farms’ profitability and offer a promising future for animal health and farm management. It’s a testament to how innovative solutions can strengthen farms and reduce the impact of challenging diseases, instilling a sense of optimism and motivation in dairy farmers. 

Study at a Glance:

  • Focus: Preventive phage therapy for Johne’s disease in dairy calves.
  • Key Innovation: Implementing bacteriophages as a new prophylactic measure against Mycobacterium avium subspecies paratuberculosis (MAP) infection.
  • Results: The study demonstrated near-complete protection for calves against MAP infection, significantly reducing fecal shedding of the pathogen.
  • Potential Impact: This approach could decrease the prevalence of Johne’s disease in dairy herds and subsequent economic losses. It aligns with global trends of reducing antibiotic use in agriculture. However, further research is needed to fully understand phage therapy’s long-term effects and potential, engaging veterinarians and animal health experts in the ongoing quest for solutions.
  • Publication Source: Journal of Dairy Science

Unveiling the Hidden Threat: Johne’s Disease in Dairy Herds

Johne’s disease is a pressing issue for the dairy industry, with significant global economic and herd health implications. It affects up to 68% of U.S. dairy herds, leading to costs of US$33 per cow annually in MAP-infected dairy herd. These costs stem from reduced milk production, early culling, lower slaughter value, and increased veterinary expenses. 

The tricky part of Johne’s disease is that it takes a long time before showing any signs, making early diagnosis difficult. Often, when signs are visible, the animal has spread the disease to others in the herd. Dr. Jeroen De Buck explains, “Johne’s disease is a hidden threat in many dairy operations. It stays unnoticed while spreading, making it tough to control.” 

Current strategies for managing Johne’s disease focus on hygiene, security, and regular testing. However, these methods are not always practical. Testing can be expensive and yield inaccurate results, complicating herd management. Dr. Emily Thompson notes, “While traditional methods provide some assistance, they are insufficient. The industry needs innovative solutions for better management of MAP infections.”

Defying Tradition: Unleashing Phages as Dairy’s Protectors

The research method was like making a custom suit: carefully choosing each part to fit perfectly. First, scientists found specific bacteriophages, which act like tiny snipers and target and destroy Mycobacterium avium subspecies paratuberculosis (MAP). In simpler terms, these bacteriophages are like ‘smart bombs’ that specifically target the harmful bacteria, leaving the beneficial bacteria unharmed. 

After mixing the bacteriophage cocktail, it became a protective shield for young calves. Think of it as giving a knight armor before a fight. The phages were given to the calves before they came into contact with MAP. They settled in the calves’ intestines, ready to attack if MAP tried to invade. 

Researchers watched the phages to see how they worked, similar to watching a nature show about predators and prey. The phages stayed in the calves’ digestive systems, providing ongoing protection against MAP. 

This new approach changes how we handle Johne’s disease. Instead of reacting after an infection starts, it stops the pathogen before it can settle in. This could change dairy cattle health strategies and disease management. 

Results: A New Hope for Johne’s Disease Prevention

The study’s impressive results show a possible breakthrough in controlling Johne’s disease. The phage therapy provided almost complete protection against MAP infection in calves, proving its high effectiveness. 

It’s important to note that bacteriophages stayed in the calves’ intestines for several weeks, providing ongoing protection against MAP. The therapy also significantly reduced MAP in feces, helping to prevent the disease from spreading in herds. 

The study showed that the phage therapy is safe, with no harmful effects on the calves. Safety is key, as concerns can slow the use of new treatments in livestock management. The calves showed no adverse reactions to the phage therapy, and their overall health and growth were unaffected, providing reassurance and confidence to dairy farmers and industry professionals. 

Dr. Emily Thompson, a veterinary expert, said, “This research might change how we handle Johne’s disease. Stopping infection before it starts could change the game for the dairy industry.”

These findings suggest that phage therapy could revolutionize the management of Johne’s disease, potentially replacing traditional control methods. This could equip dairy farmers with a potent tool to safeguard their herds’ health and production, marking a significant advancement in health management.

Charting New Horizons: Phage Therapy’s Transformative Role in Dairy Health and Economic Resilience

The economic impact of phage therapy can be measured by potential savings for a dairy farmer with a herd of 1,000 cows. Johne’s disease costs about $33 per cow annually, totaling $33,000 for the entire herd. If phage therapy reduces these costs by 50%, it could save $16,500 annually. 

Thus, adopting phage therapy for Johne’s disease could result in significant savings for dairy farmers. However, these savings depend on how well the treatment works and specific farm conditions. Phage therapy is still developing, so these savings are estimates, not definite outcomes.

Actionable Insights for Dairy Farmers: Seize the Opportunity

  • Learn and Teach: Educate yourself and your team about phage therapy. Attend workshops or webinars to stay updated on new ways to control Johne’s disease.
  • Talk to Experts: Consult with vets or researchers about dairy cattle health. Their advice can help customize phage therapy for your farm.
  • Check Herd Health: Evaluate the extent of Johne’s disease in your herd. This will help you plan how to use phage therapy effectively.
  • Set Up Protocols: Develop step-by-step guidelines for administering phage treatment to young calves, including timing and monitoring methods.
  • Monitor Effectiveness: Regularly monitor the effectiveness of phage therapy by tracking MAP levels and phage presence in calves.
  • Improve Hygiene: With phage therapy, ensure clean environments and proper manure management to reduce disease risk.
  • Cost-Benefit Check: Compare the costs of phage therapy with the benefits, such as better milk production and lower veterinary costs, to determine whether it’s cost-effective.

Navigating the Path Forward: Overcoming Barriers and Pioneering Future Research in Johne’s Disease Prevention

Translating the exciting research on phage therapy into the dairy industry faces several challenges. First up is scalability. Making a phage cocktail on a large scale is no easy task. It must be produced safely and effectively across all dairy farms, requiring new production techniques and strict quality checks. 

Then, there’s the hurdle of getting regulatory approval. Phage therapy must be proven safe and effective to be widely accepted. This means thorough testing and following strict veterinary rules. 

Future research should focus on long-term field trials. These will show the therapy’s long-term efficacy on different cattle breeds and farming methods. Mixing phage therapy with traditional methods might make disease control even better. 

There’s also room to explore broadening this therapy’s applications. It could be used for other animals or fight different germs affecting dairy herds. New techniques, like genetic engineering of phages, could help customize solutions for specific farms. 

In short, bringing phage therapy to farms isn’t simple. But the benefits—healthier herds, less economic loss, and reduced antibiotic use—show why continued research is crucial.

The Bottom Line:

This study shows a new way to fight Johne’s disease using phage therapy. This could start a new era in dairy farming that focuses on keeping herds healthy and productive. Stopping young calves from getting infected with Mycobacterium avium subspecies paratuberculosis (MAP) offers hope for more sustainable dairy farming. As this research continues, everyone in the dairy industry should stay alert and informed. 

Call to Action: Dairy farmers, vets, and experts, consider using phage therapy in your work and how it can fit into your disease management plans. Keep up with current studies and rules. Working together, we can reduce Johne’s disease and create healthier, more substantial dairy herds worldwide.

Key Takeaways:

  • Preventive phage therapy showcases the potential for shielding calves from the onset of Johne’s disease.
  • Bacteriophages exhibit sustained presence in calves’ intestines, offering prolonged defense against MAP infection.
  • Reduced fecal shedding signifies a breakthrough in disrupting the transmission loop within dairy herds.
  • As an antibiotic-free strategy, phage therapy aligns with initiatives to reduce antimicrobial usage in livestock.
  • The findings suggest a paradigm shift in traditional Johne’s management, opening doors for innovative disease control methods.

Summary:

A new study from the University of Calgary shows a promising way to fight Johne’s disease in dairy cattle. This disease, caused by a specific harmful bacteria, has been a big problem for dairy farms worldwide. The research introduces the use of phage therapy, where unique viruses are used to target and destroy these bacteria, protecting young calves from infection. If successful, this method could improve herd health and save farmers money by reducing the disease’s impact. The study found that phage therapy provides strong protection for calves, cutting down the spread of the bacteria. This could lower Johne’s disease rates in herds and help farmers avoid losing about $16,500 yearly for a herd of 1,000 cows. This approach might also help reduce the use of antibiotics in agriculture, offering a new direction for farm management.

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Reducing Johne’s Disease in US Holsteins: New Genetic Insights for Dairy Farmers

Explore how cutting-edge genetic research offers US dairy farmers a powerful tool against Johne’s disease in Holsteins. Could integrating national genetic evaluations be the breakthrough for healthier herds?

Imagine a quiet but terrible illness destroying a part of your dairy herd. Through lower milk production, veterinary expenses, and early culling, Johne’s disease (JD) is an infectious intestinal illness generating major health problems and financial losses. JD is a slow-burning catastrophe in the dairy sector, and affects farm profitability and herd health. Understanding the genetic causes of US Holsteins is not just important, it’s crucial. These discoveries, made possible by genetic research, empower farmers to choose JD-resistant features, enhancing sustainability and herd health. The role of genetic research in combating JD is significant, giving farmers the tools they need to take control of their herd’s health. Including JD resistance into national genetic campaigns helps to lower the prevalence of the illness, therefore safeguarding agricultural economy and animal welfare. This fresh research, which emphasizes the role of genetic research in combating JD, shows important genetic tendencies and provides useful advice that may completely change dairy farming methods, therefore empowering fresh waves of industry innovation and development.

Combatting Johne’s Disease: Strategies and Genomic Innovations for Dairy Farmers 

Mycobacterium avium subspecies paratuberculosis (MAP) causes the chronic bacterial illness known as Johne’s disease (JD) in dairy calves. It causes weight loss, ongoing diarrhea, lower milk output, and, finally, death. Although infection affects calves, dairy producers find it difficult because symptoms do not show until maturity.

JD affects the dairy sector with lower milk output, early culling, more veterinarian expenses, and even reputation loss. The illness may remain latent in herds for years because of a protracted incubation period during which infected cows disseminate MAP via feces, milk, and in-utero transmission.

Controlling JD typically involves:

  • Improving farm hygiene.
  • Managing calf-rearing practices.
  • Testing and culling positive animals.
  • Maintaining strict biosecurity.

These techniques have their limits. Intermittent MAP shedding means diagnostic tests often miss infections, and culling can be financially challenging, significantly if many cows are affected. 

Consider a mid-sized dairy farm in Wisconsin with 500 Holstein cows and a 5% prevalence rate of Johne’s disease. This translates to about 25 cows needing culling, each representing a financial loss of $1,500 to $2,000. Thus, the farm could initially hit $37,500 to $50,000, not including reduced milk production or veterinary costs. 

Frequent testing adds logistical hurdles and expenses. At $30 per sample, biannual testing of the entire herd could cost $30,000 annually. There’s also operational disruption from segregating infected animals, increased labor for handling and testing, and the need for continuous monitoring due to intermittent MAP shedding. 

For larger herds or multiple farms, these economic and logistical burdens grow even more. While genetic selection and advanced management practices promise long-term control of Johne’s disease, successful implementation must carefully balance costs, herd health, and farm sustainability.

Management strategies alone cannot eliminate JD. Still, its economic influence and frequency need more robust answers. Over time, a nationwide genetic examination for JD susceptibility, selective breeding of resistant cattle, and current management strategies might considerably lower Johne’s disease in dairy herds. This method emphasizes the need for genetic assessments in enhancing herd health and sustainability and presents a possible answer to a current issue.

Digging Deep: How Genetic and Phenotypic Data Can Unveil Johne’s Disease Susceptibility in US Holsteins 

Only one positive ELISA result from the first five parties was needed to classify a cow as JD-positive. This isn’t random; JD often appears in adult cows, so focusing on these early lactations captures the crucial infection period. This method ensures accuracy in detecting JD, laying a solid foundation for a reliable genetic evaluation. 

The first five lactations align with peak milk production periods, improving the precision of genetic parameter estimates. Using multiple parities ensures a comprehensive dataset, reducing the chance of false negatives. This thorough approach highlights the study’s dedication to accurately assessing JD susceptibility.

This method guarantees correct identification of sick animals and offers consistent information for genetic analyses.

To study the genetic basis of JD susceptibility, three models were used: 

  • Pedigree-Only Threshold Model (THR): This model utilizes pedigree data to estimate variance and heritability, capturing familial relationships’ contributions to JD susceptibility.
  • Single-Step Threshold Model (ssTHR): This model combines genotypic and phenotypic data, offering a precise estimate of genetic parameters by merging pedigree data with SNP markers.
  • Single-Step Linear Model (ssLR): This model uses a linear framework to combine genotypic and phenotypic data, providing an alternative perspective on heritability and genetic variance.

Unlocking Genetic Insights: Key Findings on Johne’s Disease Susceptibility in US Holsteins

The research results provide critical new perspectives on Johne’s disease (JD) sensitivity in US Holsteins, stressing hereditary factors and dependability measures that would help dairy producers address JD. Using threshold models, heritability estimates fell between 0.11 and 0.16; using a linear model, they fell between 0.05 and 0.09. This indicates some hereditary effects; however, environmental elements are also essential.

The reliability of estimated breeding values (EBVs) for JD susceptibility varied somewhat depending on techniques and models. The reliability of the IDEXX Paratuberculosis Screening Ab Test (IDX) ran from 0.18 to 0.22, and that of the Parachek 2 (PCK) protocol ran from 0.14 to 0.18. Though small, these principles are an essential initial step toward creating genetic assessments for JD resistance.

Even without direct genetic selection against JD sensitivity, the analysis revealed significant unfavorable genetic tendencies in this trait. Targeted breeding techniques allow one to maximize this inherent resilience. Including JD susceptibility in genetic assessments could help dairy producers lower JD incidence, lower economic losses, and enhance herd health.

The Game-Changer: Integrating Genetic Insights into Dairy Farming Practices 

Using these genetic discoveries in dairy farming seems to have a transforming power. Including Johne’s disease (JD) susceptibility into national genetic screening systems helps dairy producers make more educated breeding choices. Choosing cattle less prone to JD will progressively lessen its prevalence in herds, producing better cows and reducing economic losses.

Moreover, a nationwide genetic assessment system with JD susceptibility measures would provide consistent information to support thorough herd management plans. Farmers may improve herd resilience by concentrating on genetic features that support disease resistance, lowering JD frequency and related costs such as veterinary fees and lower milk output.

In the long term, these genetic developments will produce a better national Holstein population. The dairy business will become more efficient and profitable as more farmers embrace genetic assessment programs, which help lower the overall incidence of JD. Better animal welfare resulting from healthier cattle will increasingly influence consumer decisions and laws. 

These genetic discoveries provide a road forward for raising national dairy farming’s health and production standards and individual herd development. Including JD susceptibility into breeding techniques helps farmers safeguard their assets and guarantee a more lucrative and environmentally friendly future.

The Bottom Line

The analysis of Johne’s disease (JD) in US Holsteins emphasizes the use of genetic data to enhance herd health. By means of extensive datasets, insightful analysis, and stressing the relevance of this study in dairy farming, researchers have revealed vital new insights on JD susceptibility, which are, therefore, guiding breeding plans.

Recent research can benefit dairy farmers aiming to tackle Johne’s Disease (JD) in their herds. Using genetic insights and modern testing protocols, farmers can take steps to reduce this costly disease. 

Critical Steps for Dairy Farmers:

  • Regular Testing: Kits like the IDEXX Paratuberculosis Screening Ab Test (IDX) and Parachek 2 (PCK) screen milk samples from the first five parties.
  • Genetic Analysis: To gauge JD susceptibility, utilize SNP markers and models like pedigree-only threshold models or single-step models.
  • Selective Breeding: Incorporate JD susceptibility evaluation into your breeding programs to gradually reduce disease incidence.
  • Monitor Trends: Keep an eye on genetic trends in your herd and adjust breeding strategies accordingly.
  • Collaborate with Experts: Consult with geneticists and vets to understand JD’s genetic correlations with other important traits.

By adopting these strategies, dairy farmers can reduce the impact of Johne’s Disease, improving herd health and economic efficiency.

Including JD susceptibility in breeding campaigns helps produce healthier and more productive herds, lowering economic losses. Dairy producers should take these genetic elements into account when designing their breeding plans to fight JD properly.

Integration of JD susceptibility into national genetic assessments is next, and it is absolutely vital. This will simplify the choice process for JD resistance, therefore strengthening the dairy sector’s general resilience.

As a dairy farmer focused on herd health and productivity, including JD susceptibility in your breeding plans is crucial. Use these genetic insights to create a resilient dairy operationMake informed breeding choices today for a stronger future.

Key Takeaways:

  • Johne’s disease (JD) is a significant economic concern in the dairy industry, affecting ruminants globally.
  • Recent data show a 4.72% incidence rate of JD in US Holstein cattle.
  • Genetic and phenotypic data were analyzed using three models: THR, ssTHR, and ssLR.
  • Heritability estimates of JD susceptibility ranged from 0.05 to 0.16, indicating low to moderate genetic influence.
  • Reliability of genetic evaluations varied across models, with ssLR showing slightly higher reliability.
  • Despite no direct genetic selection, trends indicated a significant reduction in JD susceptibility over time.
  • Genetic correlations between JD susceptibility and other economically important traits were low, suggesting independent selection pathways.
  • Incorporating JD susceptibility into national genetic evaluations could help reduce incidence rates.

Summary:

Johne’s disease (JD) is a chronic bacterial illness affecting dairy cattle, causing weight loss, diarrhea, lower milk output, and death. It affects farm profitability and herd health, and genetic research is crucial for farmers to choose JD-resistant features. Controlling JD involves improving farm hygiene, managing calf-rearing practices, testing and culling positive animals, and maintaining strict biosecurity. However, these techniques have limitations, such as intermittent MAP shedding, which can lead to missed infections and financial challenges. A nationwide genetic examination, selective breeding of resistant cattle, and current management strategies could significantly lower JD in dairy herds. Integrating genetic insights into dairy farming practices could help producers make educated breeding choices, reduce JD prevalence, produce better cows, and reduce economic losses. In the long term, these genetic developments will lead to a better national Holstein population, making the dairy business more efficient and profitable.

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