Archive for AFM1

Anti-Mycotoxin Feed Additives Improve Milk Safety and Cattle Health Without Affecting Production

Find out how anti-mycotoxin feed additives can make milk safer and keep your cattle healthier without hurting production. Want to know how this can help your dairy farm? Keep reading.

Mycotoxins, a silent menace, pose a significant threat to animal health and milk safety in dairy farming. These toxins, produced by certain fungi, can stealthily contaminate feed and infiltrate the dairy supply chain, potentially endangering the health of cows and humans alike. 

Addressing mycotoxin contamination is crucial: 

  • Animal Health: Mycotoxins can harm cow health, causing immune and digestive problems and reducing milk production.
  • Milk Safety: Mycotoxins can endanger consumers, leading to chronic illnesses and poisoning.
  • Economic Impact: Contaminated feed decreases productivity and increases vet costs.
  • Regulatory Compliance: High mycotoxin levels can cause regulatory issues and market bans.

Being proactive in managing mycotoxins protects both livestock and the quality of dairy products. Recent research highlights that anti-mycotoxin feed additives effectively reduce toxin levels in dairy cows’ milk, urine, and blood plasma.

Confronting the Invisible Foe: Tackling Mycotoxins for Healthier Herds and Safer Milk

Mycotoxins—toxins from mold in feed—threaten livestock health and milk safety in dairy farming. Common mycotoxins like aflatoxins (AFB1), deoxynivalenol (DON), fumonisins (FUM), T-2 toxin, and zearalenone (ZEN) can harm dairy cows by affecting liver function, immunity, and overall productivity. These toxins can enter milk, posing risks to human health. 

Anti-mycotoxin feed additives such as Hydrated Sodium Calcium Aluminosilicate (HSCA) and Mycotoxin Deactivators (MD15 and MD30) have been developed to combat these dangers. These additives bind or transform mycotoxins, making them less absorbable and reducing their levels in the cow’s system. This study examines these additives’ effectiveness by measuring mycotoxin levels in milk, urine, and blood plasma, ensuring they don’t harm cow performance or nutrient absorption.

Let’s delve into the essence of the research. This study was meticulously conducted, involving twelve carefully selected multiparous cows. These cows, averaging 165 days in milk, 557 kg in body weight, and an initial milk yield of 32.1 kg/day, were grouped based on parity, milk yield, and days in milk. They were then assigned to a 4 × 4 Latin square design over 21-day periods, with the last seven days dedicated to data collection. This rigorous methodology ensures the reliability and applicability of the study’s findings to real-world dairy farming scenarios. 

The cows received different treatments to test the anti-mycotoxin feed additives: 

  • Mycotoxin group (MTX): Basal diet (BD) without additives.
  • Hydrated sodium calcium aluminosilicate (HSCA): BD plus 25g/cow/day.
  • Mycotoxin deactivator 15 (MD15): BD plus 15g/cow/day of Mycofix® Plus.
  • Mycotoxin deactivator 30 (MD30): BD plus 30g/cow/day of Mycofix® Plus.

All cows were exposed to a mycotoxin blend, including 404 μg aflatoxins B1 (AFB1), 5,025 μg deoxynivalenol (DON), 8,046 μg fumonisins (FUM), 195 μg T2 toxin (T2), and 2,034 μg zearalenone (ZEN) for the last seven days of each period. 

This setup allowed the researchers to evaluate the effects of each treatment on mycotoxin levels in milk, urine, and blood, as well as the cows’ overall performance and health.

A Closer Look at AFM1 Reduction: The Superiority of Mycotoxin Deactivators

GroupAFM1 in Milk (μg/L)AFM1 in Urine (μg/L)DON in Milk (μg/L)FUM in Plasma (μg/L)
MTX14.325.85.022.0
HSCA11.520.44.820.1
MD157.215.3N.D.12.8
MD305.68.9N.D.N.D.
N.D. = Not Detected

The study revealed significant insights, particularly in reducing milk’s aflatoxin M1 (AFM1) levels. All tested anti-mycotoxin feed additives could lower AFM1, but the mycotoxin deactivators (MD15 and MD30) outperformed the hydrated sodium calcium aluminosilicate (HSCA). 

MD30 showed the highest efficacy, achieving a more significant decline in AFM1 compared to HSCA and MD15. Moreover, mycotoxins such as deoxynivalenol (DON), fumonisins (FUM), T2 toxin (T2), and zearalenone (ZEN) were absent in the milk of cows given MD15 and MD30. However, these mycotoxins were present in cows treated with HSCA, indicating its lesser effectiveness. 

Therefore, the study highlights the superior performance of mycotoxin deactivators, especially at higher dosages, in ensuring milk safety. This underscores the importance of selecting the proper feed additives to maintain dairy herd health and ensure consumer milk safety.

The study demonstrated the substantial effectiveness of mycotoxin deactivators in reducing mycotoxin levels in dairy cows’ urine and blood plasma. Cows given MD30 had no detectable AFM1, DON, FUM, or ZEN levels in their urine, highlighting its strong mitigation effects. Similarly, cows on MD15 had lower plasma levels of FUM and ZEN, with DON being undetectable. Conversely, the HSCA group showed higher AFM1 levels, similar to the untreated MTX group. These results emphasize the efficiency of mycotoxin deactivators, particularly at higher doses, in reducing harmful mycotoxins without impacting cow health or productivity.

The findings are clear: anti-mycotoxin feed additives can reduce mycotoxin levels in milk, urine, and blood plasma without affecting milk production or nutrient absorption. These additives are crucial for promoting the health and productivity of dairy herds.

Unleashing the Power of Anti-Mycotoxin Feed Additives: Essential for a Safer and More Productive Dairy Industry 

The study highlights anti-mycotoxin feed additives’ vital role in modern dairy farming. By significantly reducing harmful mycotoxins like aflatoxin M1 (AFM1), deoxynivalenol (DON), fumonisins (FUM), T2 toxin (T2), and zearalenone (ZEN) in milk, urine, and blood plasma, these additives mitigate potential health risks. This substantial decrease protects cattle health and ensures safer dairy products for consumers. 

Remarkably, the reduction in mycotoxin levels does not affect dairy production. Cows maintained consistent milk yield and nutrient digestibility across all treatments, proving that these additives do not compromise performance. This balance between herd health and high production levels is crucial for dairy farmers. 

In practical terms, the use of mycotoxin deactivators in dairy nutrition strategies offers tangible benefits. These additives enhance milk safety and improve cattle health. By lowering mycotoxin levels, they minimize liver damage and immune suppression, thereby improving productivity and herd longevity. This directly translates to safer dairy products for consumers, enhancing the reputation and marketability of your dairy operation. 

Ultimately, the findings advocate for the widespread adoption of mycotoxin deactivators in dairy nutrition strategies. This ensures healthier herds and delivers milk of the highest safety standards, aligning with sustainable and responsible dairy farming practices in today’s food production landscape.

The Bottom Line

For dairy farmers, the use of anti-mycotoxin feed additives is a game-changer. This study’s findings highlight the effectiveness of these additives in reducing harmful mycotoxins in milk, urine, and blood plasma. They not only reduce aflatoxin M1 but also keep other dangerous mycotoxins like deoxynivalenol, fumonisins, and zearalenone undetectable in milk. Importantly, these improvements do not compromise milk production or nutrient digestibility, ensuring a win-win situation for both cattle health and dairy productivity. 

Therefore, the use of high-quality mycotoxin deactivators in feed is not just beneficial, but essential for protecting cattle health and improving dairy quality. This proactive approach empowers us to meet food safety standards and boost long-term cow productivity, ensuring a brighter future for the dairy industry. 

By adopting these proven solutions, dairy farmers can effectively tackle mycotoxin challenges, ensuring a more resilient and productive farming practice.

Key Takeaways:

  • Anti-mycotoxin feed additives significantly reduce the concentration of mycotoxins in milk, urine, and blood plasma of dairy cows.
  • Mycotoxin deactivators (MD15 and MD30) are more effective than hydrated sodium calcium aluminosilicate (HSCA) in lowering AFM1 levels in milk.
  • MD30 showed the highest efficacy, resulting in no detectable levels of AFM1, DON, FUM, T2, and ZEN in milk.
  • MD30 also demonstrated superior performance in reducing mycotoxin excretion in urine compared to HSCA and MD15.
  • Mycotoxin deactivators did not affect milk production, nutrient absorption, or blood parameters, ensuring no adverse effects on cow health or productivity.


Summary: Mycotoxins, produced by certain fungi, pose a significant threat to animal health and milk safety in dairy farming. They can contaminate feed and infiltrate the dairy supply chain, potentially endangering cows and humans. Addressing mycotoxin contamination is crucial for animal health, milk safety, economic impact, and regulatory compliance. Recent research shows that anti-mycotoxin feed additives effectively reduce toxin levels in dairy cows’ milk, urine, and blood plasma. A study on twelve multiparous cows showed that all tested anti-mycotoxin feed additives could lower AFM1, but mycotoxin deactivators (MD15 and MD30) outperformed hydrated sodium calcium aluminosilicate (HSCA). MD30 showed the highest efficacy, achieving a more significant decline in AFM1 compared to HSCA and MD15. Mycotoxins such as deoxynivalenol (DON), fumonisins (FUM), T2 toxin (T2), and zearalenone (ZEN) were absent in the milk of cows given MD15 and MD30, but were present in cows treated with HSCA, indicating lesser effectiveness. Anti-mycotoxin feed additives can reduce mycotoxin levels without affecting milk production or nutrient absorption, making them essential for modern dairy farming.

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