Archive for Genomics – Page 2

Should A.I. Companies Own Females?

The debate is back! While Artificial Insemination companies have owned females for many years, with recent dominance by some AI breeding programs on the TOP GTPI list in the US and the upcoming ability for breeders to sample their own bulls, the debate is at the forefront again!

Lessons from the Past

Over the years there have actually been many examples, with mixed results when A.I. companies have owned their own female bloodlines.

  • AltaGenetics
    Back in 2001 Alta Genetics caused considerable  stir when they planned to take their embryo program and convert it into a 1000 elite females test herd to have sires sampled through 100 contracted progeny test herds.  While the program had many supporters from the genetic advancement side, it was seen as very risky and ultimately was put on hold when Alta purchased Network Genetics.  The herd was then dispersed to farms owned by Alta in Canada and Holland and in four independent herds in the U.S.
  • GenerVations
    GenerVations is probably a great example of an A.I. program that has had a lot of success owning their own female bloodlines.  Starting with Albert Cormier’s part ownership of Skys-The-Limit Claire where he was able to maximize profits from both sides, thanks to Champion.  Continued by GenerVations part ownership of Lylehaven Lila Z, owning female bloodlines has been what enables GenerVations to compete on a global scale.  Not being able to have a large sampling program, GenerVations has had to focus on potency rather than volume.  Selecting on the very top bloodlines and putting all your eggs in a few baskets means GenerVations has to take a larger risk than the big A.I. companies.  Owning top females has helped them manage the risk.
  • Genex CRI
    The Genex CRI Genesis program has been around since 1989.  While heavily focused on top Index cattle they have been able to achieve success on the female side with such cattle as MS Pride Plnt Tasket 788-ET who tops TPI and Lifetime Net Merit lists.  On the male side, the Genex program has proven to be very stable in their bull program.  The 54 Co-op prefix bulls averaged a mere $1 drop in Lifetime Net Merit (LNM) as they transitioned from genomic-only genetic evaluations in August 2010 to daughter-proven genetic evaluations in December 2011 (minimum of 40 daughters).  The average change among the 1,879 bulls industry wide over the same time period was a $22 decrease.
  • St. Jacobs ABC
    While the St. Jacobs ABC’s Judges Choice program has been around for many years marketed in partnership with ABS Global. They have more recently entered into the ownership of top female bloodlines with the purchase of Ashlyn, Hezbollah, and Barbara.  Choosing to focus on established show cattle has meant that the Judges Choice program has been focused on young sire sales with sires achieve proven status being an added bonus.
  • Select Sires
    Probably the A.I. Company making the biggest waves today is Select Sires.  Select has been very aggressive in the ownership of top genomic females to the point that on the December Top 200 Genomic Female list they owned 18% of the top 50 new genomics heifers in the US.  With Ladys-Manor PL Shamrock and others, Select Sires is investing heavily in ownership of top genomics females in order to produce the next generation of top TPI Sires.

The Genomic Game Changer

The biggest reason this issue is coming up again is because genomics is changing the prominence of industry sires with no daughter proof data, and virgin heifers are now in heavy demand as for contract matings.  Genomics has deceased the risk to such a level that it can be very economically viable for these A.I. companies to invest in top bloodlines and increase their genetic advancement rate faster than their competition.  By being able to control the matings on these top females and use top (often unproven ) genomic sires on these virgin heifers they will be able to greatly increase their rate of advancement over their competition, and in fact fast than even top breeders.  That is because they will have access to their own top genomics young sires sooner. They  can use them on contract matings far faster than any breeder can.  This gives  them a distinct competitive advantage over both other A.I. companies and over breeders.

The Question of Ownership

A.I. companies owning females seems to be a very touchy issue for many breeders.  While many of these companies are perfectly within their rights legally, it comes down to a question of public perception.  Many companies, such as Semex, have taken a very vocal position that they do not own females.  Given that Semex is a member owned co-operative, it’s understandable that they do not want to be in competition with their breeders, many of whom are the top suppliers of sires to many A.I. companies worldwide.  However, Select Sires is also a federation of nine farmer-owned-and-controlled cooperatives.  You could not have two more extremely opposite positions from two very similarly owned companies.

The Bullvine Bottom Line

Genomics has changed the breeding world.  However, it has also created a wild wild west environment where both breeders and A.I. companies are figuring out what the new world will look like.  Will A.I. companies be nothing more than service companies that deliver genetics from many sources (much like a Wal-Mart) where they are more based on quality of service and customer experience than the genetics they have to offer?  Will more and more top breeders try to increase their own profits and sample their own sires? (Watch www.thebullvine.com for articles on these issues coming shortly)  The important  thing to note is that some A.I. companies have taken early steps to control the source and supply top genetic animals to their customers.  The world is changing and so will  the inter-relationship between breeders and A.I. companies, in many cases they are no longer just a customer they are now a competitor.

What do you think?  Leave your comments in the box below.

The Genomic Advancement Race – The Battle for Genetic Supremacy

In the race to have the next great sire, there comes a point where you have to ask have we taken it too far.  Analysis performed by Holstein International of the 33 popular genomics bulls of 2009 showed that only one has managed to maintain his breeding value: O-Style.  Even with those facts, why are so many A.I. companies now basing 70%, 80%, and 100% of their genetic programs on genomic sires?

Partly due to the “shortage” of new daughter proven sires of sons, and partly due to the increased confidence in genomics since it started in 2009 the percentage of breeding programs that are using genomic sires has increased from 40% to 50% on a global basis.  Moreover, just like a great outlier sire, the difference between the AI’s is substantial.  With Accelerated Genetics, Genex-CRI and Alta Genetics all sampling over 90% genomics sires.

So why are these studs putting so much weight in genomics?  Do they know something the rest of us don’t?  Have they just gone cuckoo?

In reality is actual goes back to the genetic advancement formula that has been around for many years.

Let’s take a close look at each piece of this equation and the effect genomics has.

Accuracy

The effect that genomics has on accuracy is very significant.  According to CDN the average gain in accuracy in LPI due to Genomics is as follows:

Sub-Group for Holstein Breed

Average LPI Reliability (%)

Traditional

Genomics

Gain

Direct Genomic Value (DGV) Weight

50K Young Bulls and Heifers
(Born 2008-2011)

37

66

29

64%

3K Heifers
(Born 2008-2011)

35

61

26

64%

Younger Cows in 1st or 2nd Lactation
(50k)

54

70

16

56%

Foreign Cows with MACE in Canada

43

68

25

61%

1st Crop Proven Sires in Canada

85

89

11

54%

Foreign Sires with MACE in Canada

70

81

11

54%

Selection Intensity

In the past AI companies would have sample multiple sires from the same cross, and try multiple crosses to find out which one was the genetically gifted.  That does not even take into account the need to sample from a larger portion of the top females to discover which ones where genetically gifted and which ones where “artificial” in their breeding values.  With genomics, they can pre-screen these sires and crosses to see which ones will have the highest chance of producing the next top-selling sire and which ones did not get the best their parents had to offer.

By eliminating the need to sample such a large number of sires, allows the AI companies to focus on a more intense core group of sires, and push the limits on genetics advancement

Genetic Variability

This is one area than many breeders do not pay enough attention to.  Certain traits, such as Milk Yield, Protein Yield, and stature are much more heritable than others (i.e. Rump and Feet & Legs).  What this means is, if you spent all your time breeding for feet and legs, you will see less overall genetic gain than say focusing on production traits.  That is why production sires will typically offer the greatest genetic gain, since most type traits have a much lower heritability.  It’s also why breeders always need to be conscious of production when building your breeding program and don’t mate for low heritability traits.

The following is Holstein heritability estimates used for genetic evaluations in Canada

  • Production Traits
    • Milk Yield 43%
    • Fat Yield  34%
    • Protein Yield 40%
    • Fat Percentage 50%
    • Protein Percentage  50%
  • Functional Traits
    • Somatic Cell Score  27%
    • Lactation Persistency 40%
    • Herd Life  10%
    • Calving Ability 6%
    • Daughter Calving Ability 6%
    • Milking Speed  21%
    • Milking Temperament 13%
    • Daughter Fertility 7%
  • Major Type Traits
    • Conformation 26%
    • Rump 15%
    • Mammary System 25%
    • Dairy Strength 36%

Time

In order to cut down the genetic intervals many AI companies are now using genomic sires themselves as sires of sons.  This means that there are sires of sons that don’t have any daughter information yet.  The company taking this to the extreme is Alta Genetics.  Their breeding program is made up by no less than 70% of genomic bulls that are sired by genomic bulls.  The greater you can cut down the interval from the birth of the parent to the birth of the progeny the greater the average genetic gain per year.Yes, you will run the risk of sires that drop, but overall on a large breeding program you will come out ahead.

The Bullvine Bottom Line

Many AI companies, especially in North America, are pushing the edge with genomics to maximize annual genetic gain.  While they will run the risk of a sire not turning out, or dropping significantly from his pre-proven prediction, when you look at the net result over the generations of their whole breeding program they will come out way ahead.  By leveraging the effect Genomics has on accuracy, selection intensity, focusing on highly heritable traits, and making the interval between generations as low as possible, these studs stand the greatest chance of consistently producing the best genetics available.
The Dairy Breeders No BS Guide to Genomics

 

Not sure what all this hype about genomics is all about?

Want to learn what it is and what it means to your breeding program?

Download this free guide.

Not Sure Which Genomic Young Sire To Use?

If you are like many, this whole genomics thing can be very confusing.  While it might be just simplest to pick the top five genomic young sires.  Who knows what could happen.  In order to get some clarity on just what young sires you should use we took a deeper look at the top 50 genomic young sires available in Canada and here is what we found.

GLPI vs Parent Average

In the past most would have just simply used the top parent average young sires and gone from there.  It’s interesting to see that only one of the top GPA LPI sires (DE-SU PHOENIX 588-ET) would have even been considered a top LPI sire before genomics.

GPA LPI PA-LPI
DE-SU PHOENIX 588-ET GEN-I-BEQ LAVAMAN
GENERVATIONS LEXOR COMESTAR LOBSTER
CABON FERNAND COMESTAR LAUTAMARCUS
MISTY SPRINGS NUMBER ONE DE-SU PHOENIX 588-ET
COOKIECUTTER HEFTY-ET STE ODILE RIMOUSKI

Genomically Gifted

With DE-SU PHOENIX 588-ET jumping to the top of the list, we then wanted to see just who else has been genomically gifted with the best genes his parents have to offer. What we found was the following:

Sire GPA LPI PA – LPI Difference Direct Genomic Value
CABON FERNAND 3239 2492 747 3655
DE-SU ALTAROGERS-ET 2816 2159 657 3167
COOKIECUTTER HEFTY-ET 3211 2591 620 3211
DE-SU ALTAMELHOR-ET 3013 2413 600 3296
SHEEKNOLL ALTAVITTEK 2905 2307 598 3291

Bitch Slapped With the Ugly Stick

Since we took the time to see who was gifted we thought it would be equally important to see what bulls full-out of the ugly tree and hit every branch on the way down.  Here is what we found:

Sire GPA LPI PA LPI Difference Direct Genomic Value
COMESTAR LAUTAMARCUS 2879 3020 -141 2806
GIBBS M-M DENALLI-ET 2913 2909 4 2847
COMESTAR LOBSTER 3048 3020 28 3094
GEN-I-BEQ LAVAMAN 3116 3070 46 3317
GENERVATIONS LINGO 2938 2888 50 2899

(Please note: this does not mean they are totally ugly they are just not as pretty as the could have been)

When in Doubt Go To Sire Stack

One thing I have learned from your tried and true breeders, is whether you are breeding for index or showing, nothing beats a good sire stack.  With that in mind we prepared a 4 generation sire stack of each sire and here is the cream of the crop.

Sire Sire Stack Sire Stack Index
DE-SU PIERRE 649-ET Planet x Bolton x Shottle x Justice 2638
PIROLO SOLEMIO-ET Man-O-Man x Goldwyn x Justice x Jacko Besn 2617
GENERVATIONS ENSIGN Man-O-Man x Baxter x Shottle x Justice 2582
ESPOIR Man-O-Man x Goldwyn x Champion x Jesther 2573
GALLAIS FEELING Man-O-Man x Bolton x Shottle x Trent 2565

Girl Power

The following are the bulls that are getting it done from a strong female (dam) side of their pedigree.

Sire GPA LPI Sire Stack Index Difference
MAPEL WOOD BREWMASTER 3046 1955 1091
MISTY SPRINGS SUPERSONIC 2827 1760 1067
DE-SU ALTAMELHOR-ET 3013 2084 929
LESPEREE GLOBAL 3009 2099 910
MISTY SPRINGS NUMBER ONE 3220 2331 889

The Bottom Line

Depending on your propensity for risk you can take those sires that are the extreme genomically, such as CABON FERNAND or DE-SU ALTAROGERS-ET, or you can go for the sire with great blood lines, such as DE-SU PIERRE 649-ET and PIROLO SOLEMIO-ET.  But as my wife tells me every day, behind every good man is a great woman, so maybe you try MAPEL WOOD BREWMASTER or MISTY SPRINGS SUPERSONIC.

 

The Dairy Breeders No BS Guide to Genomics Not sure what all this hype about genomics is all about?

Want to learn what it is and what it means to your breeding program?

Download this free guide.

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